Measurement of substrate thermal resistance using DNA denaturation temperature

Heat Transfer and Thermal Management have become important aspects of the developing field of uTAS systems particularly in the application of the the uTAS philosophy to thermally driven analysis techniques such as PCR. Due to the development of flowing PCR thermocyclers in the field of uTAS, the authors have previously developed a melting curve analysis technique that is compatible with these flowing PCR thermocyclers. In this approach a linear temperature gradient is induced along a sample carrying microchannel. Any flow passing through the microchannel is subject to linear heating. Fluorescent monitoring of DNA in the flow results in the generation of DNA melting curve plots. This works presents an experimental technique where DNA melting curve analysis is used to measure the thermal resistance of microchannel substrates. DNA in solution is tested at a number of different ramp rates and the di®erent apparent denaturation temperatures measured are used to infer the thermal resistance of the microchannel substrates. The apparent variation in denaturation temperature is found to be linearly proportional to flow ramp rate. Providing knowledge of the microchannel diameter and a non-varying cross-section in the direction of heat flux the thermal resistance measurement technique is independent of knowledge of substrate dimensions, contact surface quality and substrate composition/material properties. In this approach to microchannel DNA melting curve analysis the difference between the measured and actual denaturation temperatures is proportional to the substrate thermal resistance and the ramp-rate seen by the sample. Therefore quantitative knowledge of the substrate thermal resistance is required when using this technique to measure accurately DNA denaturation temperatur

Mexican footprints in Spanish film: magical and resistent nature in Alejandro González Iñárritu's Beautiful and Guillermo del Toro’s Pan’s laberinth

Guillermo del Toro y Alejandro González lñárritu son de los protagonistas más conocidos del movimiento transnacional en los cines mexicanos e hispanos del nuevo siglo. Sus éxitos tanto en su país de origen como en España y Estados Unidos atestiguan de sus habilidades y su visión. El presente estudio descubre una estética latinoamericana y mexicana acerca del papel de la naturaleza y el paisaje nacional que aparece en su cine español.Guillermo del Toro and Alejandro González lñárritu sit at the fore of the transnational shift in Mexican and Hispanic cinemas of the new century. Their successful films both at home and in Spain and the US have attested to their skill as auteurs and visionaries. The present study uncovers the Latín American and Mexican aesthetics surrounding the role of nature and the national landscape in these directors' Iberian films

Henri Temianka Correspondence; (ddalton)

This collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/1803/thumbnail.jp

Henri Temianka Correspondence; (ddalton)

This collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/1802/thumbnail.jp

Henri Temianka Correspondence; (ddalton)

This collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/1800/thumbnail.jp

STABILIZATION OF UPLAND RICE PRODUCTION UNDER SHORTENED FALLOW IN WEST AFRICA: RESEARCH PRIORITY SETTING IN A DYNAMIC ENVIRONMENTAL AND ECONOMIC CLIMATE

This paper presents a dynamic model of land resource degradation and shifting rice cultivation in West Africa based upon Boserup and Dvorak. The model indicates the ex ante impact of research strategies to maximize the economic benefits of host plant resistance and land resource management and thereby stabilize yield decline and reduce land degradation.Land Economics/Use, Resource /Energy Economics and Policy,